Human biology is an interdisciplinary area of academic study that examines humans through the influences and interplay of many diverse fields such as genetics, evolution, physiology, anatomy, epidemiology, anthropology, ecology, nutrition, population genetics, and sociocultural influences. It is closely related to the biomedical sciences, biological anthropology and other biological fields tying in various aspects of human functionality. It wasn't until the 20th century when biogerontologist, Raymond Pearl, founder of the journal Human Biology, phrased the term "human biology" in a way to describe a separate subsection apart from biology.It is also a portmanteau term that describes all biological aspects of the human body, typically using the human body as a type organism for Mammalia, and in that context it is the basis for many undergraduate University degrees and modules.Most aspects of human biology are identical or very similar to general mammalian biology. In particular, and as examples, humans : maintain their body temperature have an internal skeleton have a circulatory system have a nervous system to provide...

Astrobiology, and the related field of exobiology, is an interdisciplinary scientific field that studies the origins, early evolution, distribution, and future of life in the universe. Astrobiology is the multidisciplinary field that investigates the deterministic conditions and contingent events with which life arises, distributes, and evolves in the universe. Astrobiology makes use of molecular biology, biophysics, biochemistry, chemistry, astronomy, physical cosmology, exoplanetology, geology, paleontology, and ichnology to investigate the possibility of life on other worlds and help recognize biospheres that might be different from that on Earth. The origin and early evolution of life is an inseparable part of the discipline of astrobiology. Astrobiology concerns itself with interpretation of existing scientific data, and although speculation is entertained to give context, astrobiology concerns itself primarily with hypotheses that fit firmly into existing scientific theories. This interdisciplinary field encompasses research on the origin of planetary systems, origins of organic compounds in space, rock-water-carbon...

PLOS Biology is a monthly peer-reviewed scientific journal covering all aspects of biology. Publication began on October 13, 2003. It is the first journal published by the Public Library of Science. The editor-in-chief is Nonia Pariente.In addition to research articles, the journal publishes magazine content aimed to be accessible to a broad audience. Article types in this section are essays, "unsolved mysteries", editorials, and synopses. Abstracting and indexing The journal is abstracted and indexed in: Biological Abstracts BIOSIS Previews Current Contents/Agriculture, Biology & Environmental Sciences Current Contents/Life Sciences Chemical Abstracts Service Embase Index Medicus/MEDLINE/PubMed Science Citation Index Scopus The Zoological RecordAccording to Journal Citation Reports, the journal had a 2019 impact factor of 7.076. The journal does not list this impact factor on its website. Instead, the journal promotes the use of article level metrics to provide...

An endosymbiont or endobiont is any organism that lives within the body or cells of another organism most often, though not always, in a mutualistic relationship. (The term endosymbiosis is from the Greek: ἔνδον endon "within", σύν syn "together" and βίωσις biosis "living".) Examples are nitrogen-fixing bacteria (called rhizobia), which live in the root nodules of legumes, single-cell algae inside reef-building corals and bacterial endosymbionts that provide essential nutrients to insects.The history behind the concept of endosymbiosis stems from the postulates of the endosymbiotic theory. The endosymbiotic theory (symbiogenesis) pushes the notion of bacteria exclusively living in eukaryotic organisms after being engulfed by them. This is popular with the concept of organelle development observed with eukaryotes. Two major types of organelle in eukaryotic cells, mitochondria and plastids such as chloroplasts, are considered to be bacterial endosymbionts.There are two types of symbiont transmissions. In horizontal transmission, each new generation acquires free living symbionts from...

Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the lambda virus. As well as inserting genes, the process can be used to remove, or "knock out", genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome.An organism that is generated through genetic engineering is considered to be genetically modified (GM) and the resulting entity is a genetically modified organism (GMO). The first GMO was a bacterium generated by Herbert Boyer and...

In biology, abiogenesis (from a- 'not' + Greek bios 'life' + genesis 'origin') or the origin of life is the natural process by which life has arisen from non-living matter, such as simple organic compounds. The prevailing scientific hypothesis is that the transition from non-living to living entities on Earth was not a single event, but a process of increasing complexity involving the formation of a habitable planet, the prebiotic synthesis of organic molecules, molecular self-replication, self-assembly, autocatalysis, and the emergence of cell membranes. Many proposals have been made for different stages of the process. The study of abiogenesis aims to determine how pre-life chemical reactions gave rise to life under conditions strikingly different from those on Earth today. It primarily uses tools from biology and chemistry, with more recent approaches attempting a synthesis of many sciences. Life functions through the specialized chemistry of carbon and water, and builds largely upon four key families of chemicals: lipids for cell membranes, carbohydrates such as sugars, amino acids for protein metabolism, and nucleic acid...

Cheating is a term used in behavioral ecology and ethology to describe behavior whereby organisms receive a benefit at the cost of other organisms. Cheating is common in many mutualistic and altruistic relationships. A cheater is an individual who does not cooperate (or cooperates less than their fair share) but can potentially gain the benefit from others cooperating. Cheaters are also those who selfishly use common resources to maximize their individual fitness at the expense of a group. Natural selection favors cheating, but there are mechanisms to regulate it. The stress gradient hypothesis states that facilitation, cooperation or mutualism should be more common in stressful environments, while cheating, competition or parasitms are common in benign environments (i.e nutrient excess). Theoretical models Organisms communicate and cooperate to perform a wide range of behaviors. Mutualism, or mutually beneficial interactions between species, is common in ecological systems. These interactions can be thought of "biological markets" in which species offer partners goods that are relatively inexpensive for them to produce...

A neuron, neurone, or nerve cell is an electrically excitable cell that fires electric signals called action potentials. Neurons communicate with other cells via synapses - specialized connections that commonly use minute amounts of chemical neurotransmitters to pass the electric signal from the presynaptic neuron to the target cell through the synaptic gap. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are functionally connected together, they form what is called a neural circuit. ...

Aristotle's biology is the theory of biology, grounded in systematic observation and collection of data, mainly zoological, embodied in Aristotle's books on the science. Many of his observations were made during his stay on the island of Lesbos, including especially his descriptions of the marine biology of the Pyrrha lagoon, now the Gulf of Kalloni. His theory is based on his concept of form, which derives from but is markedly unlike Plato's theory of Forms. The theory describes five major biological processes, namely metabolism, temperature regulation, information processing, embryogenesis, and inheritance. Each was defined in some detail, in some cases sufficient to enable modern biologists to create mathematical models of the mechanisms described. Aristotle's method, too, resembled the style of science used by modern biologists when exploring a new area, with systematic data collection, discovery of patterns, and inference of possible causal explanations from these. He did not perform experiments in the modern sense, but made observations of living animals and carried out dissections. He names some 500 species of bird, mammal, and...

Nuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes. The field was pioneered by Richard R. Ernst and Kurt Wüthrich at the ETH, and by Ad Bax, Marius Clore, Angela Gronenborn at the NIH, and Gerhard Wagner at Harvard University, among others. Structure determination by NMR spectroscopy usually consists of several phases, each using a separate set of highly specialized techniques. The sample is prepared, measurements are made, interpretive approaches are applied, and a structure is calculated and validated. NMR involves the quantum-mechanical properties of the central core ("nucleus") of the atom. These properties depend on the local molecular environment, and their measurement provides a map of how the atoms are linked chemically, how close they are in space, and how rapidly they move with respect to each other. These properties are fundamentally the same as those used in the more familiar magnetic resonance imaging (MRI), but the molecular applications...